DYC Chemistry Professor Recognized for Spin Crossover Research
Dr. Margaret A. Goodman has recently received international recognition from the noted journal Inorganic Chimica Acta
Buffalo, New York – October 6, 2014 – The cutting edge research in the field of spin crossover by Margaret A. Goodman, PhD, associate professor of chemistry at D’Youville, has recently received international recognition from the noted journal Inorganic Chimica Acta.
Goodman works on the design of molecular switches, similar to molecules and enzymes that function similarly in biology, opening up possibilities in the fields of nanotechnology, biomedicine and computer chip design.
A journal reviewer stated, “They prepare for the first time…a ligand that a number of us have failed previously to make and actually said was not possible…” “Overall this paper will be one of the most referenced ICA papers this year.”
“This technology has many applications, for example they can assist in drug design and delivery, or to indicate dangerous potential radiation or poison exposure,” said Dr. Marion Pace Olivieri, chair of the Department of Math and Natural Sciences at the college.
A molecular switch is a molecule that can be reversibly shifted between two or more stable states. It may be shifted between the states in response to environmental stimuli, such as changes in pH, light, temperature, an electrical current, microenvironment, or in the presence of a ligand (an attached atom or molecule).
These switches are also important in biology as many biological functions are based on it, for instance allosteric regulation and vision. They are also one of the simplest examples of molecular machines, according to biology experts.
Goodman states that, “to me, one of the most rewarding feelings is when you’re finally able to synthesize your target molecule. Knowing that I was able to come up with a successful synthetic path where others have failed is incredibly satisfying.”
Last summer, University of Cambridge scientists identified and ‘on/off’ switch in a type of cancer, which typically occurs in the testes and ovaries called “malignant germ cell tumors.” The cancerous tumors are seen in patients of all ages, both in childhood and adulthood,” according to Medical Xpress, an online medical and health news service.
Goodman is a summa cum laude graduate of the University at Buffalo where she earned her Ph.D. in chemistry. She was selected ‘Faculty Member of 2013’ at D’Youville and received the Faculty Council Penelope Klein Research Fellowship in 2012. She has published extensively and presented her research nationwide.