"My research utilizes cell and molecular biology to investigate how oxidative stress can serve as a tool to promote cell death in cancer cells. "
I completed my graduate work at Albert Einstein College of Medicine in the laboratory
of Dr. Susan Band Horwitz, who discovered the anti-cancer drug, taxol.
For my doctoral thesis, I worked on the regulation of the protein that causes multidrug resistance in cancer cells. My research utilizes cell and molecular biology to investigate how oxidative stress can serve as a tool to promote cell death in cancer cells. I collaborate with a team of electrical engineers at the University at Buffalo who generate free radicals in the form of non-thermal plasma. Working together with students from D'Youville, we investigate how combinations of genetic manipulations, drug therapy and non-thermal plasma can selectively target melanoma cells.
Currently, I have three D'Youville students working on research projects with me. I supervise the students closely and assign independent projects in the areas of tissue culture and the effects of pharmaceutical agents on melanoma cell death. I also maintain active collaborations with researchers at Roswell Park Cancer Institute.
In addition to my research, I am very enthusiastic about teaching. I am the instructor for first year PharmD. students in the Anatomy, Physiology, and Pathophysiology course (APP) at DYC. I also assist teaching in the Introduction to Collaborative Learning Course (CLIP).
DYC is very unique in how interactive the courses are. For example, when the students learn about heart rate in APP, they are simultaneously learning how to take blood pressure in Patient Assessment, and about treatment for arrhythmias in CLIP. This approach really helps the students to integrate their knowledge.
I've found DYC students to be motivated and eager to learn. There is a strong focus on team learning, enabling individuals to share their strengths. They really work well together and the camaraderie is very positive.
Shoshanna N. Zucker, PhD
School of Pharmacy